HPE ProLiant DL385 Gen11 2U 8x 2.5in SFF AMD EPYC 9004/9005 Server (CTO) front view

HPE

HPE ProLiant DL385 Gen11 2U 8x 2.5in SFF AMD EPYC 9004/9005 Server (CTO)

Part number: P53921-B21

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Overview

The HPE ProLiant DL385 Gen11 is the AMD-based counterpart to the DL380 Gen11: a 2U, two-socket server for EPYC 9004 and 9005 series processors. It is sold configure-to-order and is chosen for high-core-count virtualization, containers, analytics and GPU workloads. This listing uses the 8 SFF chassis, HPE part P53921-B21.

HPE's QuickSpecs list processors with up to 160 cores. The server has 24 DDR5 DIMM slots, 12 per processor with one DIMM per channel, and a maximum of 6TB of RDIMM memory when both sockets are filled. HPE quotes memory speeds of up to 6400 MT/s. The P53921-B21 chassis includes an eight-bay SFF drive cage. HPE also sells 8 LFF, 12 EDSFF, 48 SFF and GPU-optimized versions. Controllers are the Gen11 MegaRAID range: MR216i-o, MR408i-o and MR416i-o in OCP form, MR216i-p and MR416i-p as PCIe cards, plus the MR932i-p and SR932i-p.

Networking is a choice of OCP or PCIe stand-up card. One PCIe slot is standard on the primary riser, and the server reaches up to eight slots with two processors. HPE lists support for eight single-wide or four double-wide GPUs. Flex Slot power supplies go from 800W to 1800-2200W, including a 1600W -48VDC unit, and iLO 6 handles management.

ICT Devices quotes the DL385 Gen11 from the configuration you send and supplies today's price on request. Check the following first.

  • EPYC 9004 or 9005 series, since supported memory speed differs by processor
  • One or two processors: slot count and memory capacity both depend on it
  • DIMM size, with all 12 channels per CPU populated where possible
  • Risers needed for your PCIe cards and GPUs
  • Network card type and power supply rating

Specifications

Form factor2U rack
CPU supportAMD EPYC 9004 and 9005 Series, processors with up to 160 cores
Max CPUs2
Memory slots24 DDR5 DIMM slots (12 per processor, 1 DIMM per channel)
Max memory6TB RDIMM with two processors
Memory typeHPE DDR5 Smart Memory RDIMM, up to 6400 MT/s
Drive bays8 SFF cage included; other chassis offer 8 LFF, 12 EDSFF or 48 SFF
Storage controller optionsHPE MR216i-o, MR408i-o, MR416i-o (OCP); MR216i-p, MR416i-p, MR932i-p, SR932i-p (PCIe); external E208e-p
PCIe slots1 standard on primary riser; up to 8 with two processors
GPU supportUp to 8 single-wide or 4 double-wide GPUs
NetworkChoice of OCP or PCIe stand-up network card
Power suppliesHPE Flex Slot hot-plug: 800W Platinum, 1000W Titanium, 1600W Platinum, 1600W -48VDC, 1800-2200W Titanium
ManagementHPE iLO 6
Base SKU / modelP53921-B21 (HPE ProLiant DL385 Gen11 8SFF CTO Server)

Frequently asked questions

How does the DL385 Gen11 differ from the DL380 Gen11?

The DL385 uses AMD EPYC 9004 and 9005 processors and has 24 DIMM slots with 12 memory channels per CPU. The DL380 uses Intel Xeon Scalable processors and has 32 DIMM slots with 8 channels per CPU.

Can I run it with one processor?

Yes, but some resources depend on the second CPU. HPE lists the 6TB memory maximum and the eight-slot PCIe maximum with two processors installed.

How many GPUs can it take?

HPE's QuickSpecs describe the chassis as supporting eight single-wide or four double-wide GPUs. HPE also lists a dedicated GPU CTO chassis, P54198-B21, for GPU-first builds.

Which other CTO chassis exist?

HPE lists P53925-B21 for 8 LFF, P53929-B21 for 12 EDSFF, P54198-B21 for GPU and P57844-B21 for 48 SFF.

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